For patients
Rituximab
anti-CD20, RTX
Are you a clinician? See the clinical version of this page.
The short versionRituximab is usually planned so that it is given before pregnancy rather than during it. Given later in pregnancy, it can lower the baby's immune cells for a while, so the baby's live vaccines may be timed differently. It is generally considered compatible with breastfeeding.
- The plan is usually to give rituximab before pregnancy, not during it.
Through your pregnancy journey
Use if needed
Before pregnancy
Often given before pregnancy, with conception planned afterwards.
Use if needed
First trimester
Inadvertent early exposure is generally low risk; deliberate use is usually avoided.
Avoid
Second & third trimester
Usually avoided later in pregnancy unless a mother has serious disease that needs it.
Continue
Breastfeeding
Considered compatible with breastfeeding.
Continue
For fathers-to-be
Considered compatible for fathers-to-be.
iThis page helps you prepare a conversation with your care team. It does not replace individual medical advice. Always confirm your own plan with your rheumatology and pregnancy team.
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When to call your team
- Tell your baby's care team if you received rituximab in pregnancy, so vaccines can be planned.
- Do not change your treatment without talking to your team.