For patients
NSAIDs
ibuprofen, naproxen, non-steroidal anti-inflammatory drugs
Are you a clinician? See the clinical version of this page.
The short versionNSAIDs like ibuprofen can be used for short periods in early and mid pregnancy if needed, but are stopped in the later part of pregnancy because they can affect the baby's circulation and the fluid around the baby. If you are trying to conceive, heavy use can make it harder to fall pregnant.
- Stop NSAIDs in the last part of pregnancy unless your team specifically advises otherwise.
- If you are trying to conceive, heavy NSAID use may make it harder.
Through your pregnancy journey
Use if needed
Before pregnancy
Can be used short-term, but heavy use may make it harder to conceive; discuss if you are trying.
Use if needed
First trimester
Can be used for short periods if needed.
Avoid
Second & third trimester
Used only now and then earlier in pregnancy, and stopped after 28 weeks.
Continue
Breastfeeding
Considered compatible with breastfeeding (for example ibuprofen).
Continue
For fathers-to-be
Considered compatible for fathers-to-be.
iThis page helps you prepare a conversation with your care team. It does not replace individual medical advice. Always confirm your own plan with your rheumatology and pregnancy team.
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When to call your team
- Stop NSAIDs in the later part of pregnancy unless your team advises otherwise.
- Ask your team what to use for pain relief in the third trimester.
- Mention NSAID use if you are having difficulty conceiving.